Malignant hyperthermia: pharmacology of triggering
نویسندگان
چکیده
منابع مشابه
Malignant hyperthermia: pharmacology of triggering.
Over the past 50 yr, many drugs have been implicated as triggers of malignant hyperthermia (MH), a potentially fatal pharmacogenetic disorder of skeletal muscle calcium regulation. This review discusses the potent inhalation agents as the principal triggers and evidence that the modern agents, desflurane, sevoflurane, and isoflurane, can cause florid MH reactions in the same way as halothane bu...
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Letter to the Editor concerns the question of a discussion of awake porcine malignant hyperthermia that erroneously omits the awake human stress reaction of malignant hyperthermia.
متن کاملMalignant Hyperthermia
''Malignant Hypothermia'' syndrome is a rare, but dangerous occurrence, the aetiology of which is not known. Up to this date 180 cases have been reported. This syndrome i's seen generally in :male children over age of two years, and especially in adolescent males. Also those people with muscular abnormalities are more susciptable to this illnes'S. Anaesthetic agent such as halothane or muscular...
متن کاملEstimate of the relative risk of succinylcholine for triggering malignant hyperthermia.
BACKGROUND Facilities with volatile anesthetic agents stock dantrolene for the treatment of malignant hyperthermia (MH). The availability of dantrolene at these facilities satisfies cost-utility norms even for sites with as few as 1 anesthetic per workday, based on the overall incidence of MH per anesthetic. We considered the stocking of dantrolene at facilities with succinylcholine alone (i.e....
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Malignant hyperthermia is a rare and fatal disorder. A 16-year-old male patient was a candidate for rhinoplasty surgery with no history of disease and previous surgery, negative family history and no history of medication use in the operating room. Maintenance of anesthesia was performed with O2, NO2 (50% -50%) and MAC isoflurane 1. Gradually, from the 80th minute after the start of the operati...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2011
ISSN: 0007-0912
DOI: 10.1093/bja/aer132